Limited Evidence Base: 

While some studies and anecdotal evidence suggest potential benefits of GcMAF, rigorous clinical trials are lacking. 

Its use is not approved by major regulatory bodies, and claims are often controversial. 

Nagalase and GcMAF Connection: 

High nagalase activity is a central focus in many conditions. GcMAF’s theoretical benefits arise from its ability to counteract nagalase’s immune-suppressive effects. 

Caution: 

Due to the experimental nature of GcMAF, it should only be used under strict medical supervision and after thorough consideration of existing scientific evidence.